Chloromethyl methyl ethe
CHLOROMETHYL METHYL ETHER
CAS: 107-30-2
Molecular Formula: C2H5ClO
Chloromethyl methyl ethe - Names and Identifiers
Chloromethyl methyl ethe - Physico-chemical Properties
| Molecular Formula | C2H5ClO |
| Molar Mass | 80.51 |
| Density | d420 1.0605 |
| Melting Point | -103.5°C |
| Boling Point | bp 59° |
| Flash Point | 15℃ (tag closed test) |
| Water Solubility | decomposes |
| Solubility | Chloroform (Sparingly), Methanol (Slightly) |
| Vapor Presure | 260 mmHg at 20 °C |
| Appearance | Colorless liquid |
| Color | Colourless to Light Yellow |
| Odor | Similar to HCl |
| Exposure Limit | TLV-TWA — none assigned, A2-SuspectedHuman Carcinogen (ACGIH 1988); Carcinogen–Human Limited Evidence (IARC); Carcinogen (OSHA). |
| Storage Condition | 2-8°C |
| Refractive Index | nD20 1.39737 |
| Physical and Chemical Properties | Colorless transparent liquid. Melting Point -103.5 °c, boiling point 59 °c (59.1 °c), relative density 1.07(20/4 °c), refractive index 1.39737, flash point 15 °c. Decomposition in water, soluble in ethanol, acetone, ethyl benzene, benzene and chloroform. Irritating odor, easy to flow, volatile. The patient was found to be lacrimal. |
| Use | Active organic intermediates. Chloromethyl agent, mainly used for the production of anion exchange resin, also used for the production of sulfadiazine drugs. |
Chloromethyl methyl ethe - Risk and Safety
| Hazard Symbols | F - Flammable T - Toxic  |
| Risk Codes | R45 - May cause cancer R11 - Highly Flammable R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
| Safety Description | S53 - Avoid exposure - obtain special instructions before use. S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) |
| UN IDs | UN 1239 |
| Toxicity | LC50 inhal (rat) 55 ppm (180 mg/m3; 7 h) LD50 oral (rat) 817 mg/kg |
Chloromethyl methyl ethe - Nature
Open Data Verified Data
colorless transparent liquid, volatile, irritating odor, with tear. Melting Point -103.5 °c. Boiling point of 59 degrees C (59.1 degrees C). Relative density (d20)1. 07. Refractive index 1. 39737 (1. 3974). Decomposition in water, soluble in ethanol, acetone, ethyl benzene, benzene and chloroform.
Last Update：2024-01-02 23:10:35
Chloromethyl methyl ethe - Preparation Method
Open Data Verified Data
The mixture of methanol and formaldehyde was reacted with hydrogen chloride gas. The raw materials and tail gas in the production process contain hydrogen chloride, which causes serious corrosion to the equipment. At present, domestic production uses water to absorb hydrogen chloride in the tail gas to increase by-products and reduce pollution.
Last Update：2022-01-01 10:16:11
Chloromethyl methyl ethe - Use
Open Data Verified Data
chloromethyl agent, mainly used in the production of anion exchange resin, also used in the production of pharmaceutical sulfadiazine.
Last Update：2022-01-01 10:16:12
Chloromethyl methyl ethe - Safety
Open Data Verified Data
- highly toxic substances are carcinogens. In particular, the by-product dichloromethyl ether is more toxic and has strong irritation. The maximum allowable concentration in air is 1 × 10 -6. To strengthen equipment maintenance and repair, to prevent running, run, drop, leakage. Good ventilation should be maintained at the production site. When chloromethyl ether comes into contact with the human body, it is advisable to rinse with water. The operator should wear protective gear.
- It is packed in a polyethylene barrel, and good sealing is required. Store in a dry, cool, ventilated place, sunscreen, moisture-proof. According to the provisions of the storage and transportation of toxic chemicals.
Last Update：2022-01-01 10:16:12
Chloromethyl methyl ethe - Reference Information
Open Data Unverified Data
| (IARC) carcinogen classification | 1 (Vol. 4, Sup 7, 100F) 2012 |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |
Last Update：2024-04-16 09:14:08
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Chloromethyl methyl ethe
2-甲基-3-氨基-5-硝基吡啶
2-氨基-3-硝基-5-甲基吡啶
(4S)-6,7-DIFLUOROCHROMANE-4-YLAMINE
异硫氰酸异丁酯
4-甲氧基-3-甲基苯酚
苯并[D]噻唑-2-甲酸乙酯
ACID BLUE 41
1-硬脂酰-2-亚油酰磷脂酰乙醇胺(SLinPE)
丁基三甲氧基硅烷
2-甲基-3-氨基-5-硝基吡啶
2-氨基-3-硝基-5-甲基吡啶
(4S)-6,7-DIFLUOROCHROMANE-4-YLAMINE
异硫氰酸异丁酯
4-甲氧基-3-甲基苯酚
苯并[D]噻唑-2-甲酸乙酯
ACID BLUE 41
1-硬脂酰-2-亚油酰磷脂酰乙醇胺(SLinPE)
丁基三甲氧基硅烷